All Diagnostic Divisions
Division I

Clinical Chemistry & Metabolic Profiling

Precision clinical chemistry with two fully automated Beckman Coulter analyzers, delivering high-throughput metabolic, renal, hepatic, and glycemic panels with real-time STAT priority.

Beckman Coulter AU480DxC 700 AUISE Potentiometry
Turnaround Time
2–6 hours (STAT: < 45 min)
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Division Mandate & Scientific Scope

Our Clinical Chemistry department is anchored by two automated clinical chemistry analyzers from Beckman Coulter: the high-throughput DxC 700 AU and the versatile AU480. Combining precision spectrophotometry and Ion-Selective Electrode (ISE) potentiometry, the platform delivers quantitative analysis for organ function, critical electrolyte balance, and glycemic control. The division processes an extensive advanced chemistry menu including CRP, GGT, Advanced HbA1c, IgA immunoglobulins, complete electrolyte panels, CK-NAC, CK-MB mass, complement proteins (C3 and C4), lipid panels, Rheumatoid Factor (RF), Anti-Streptolysin O (ASO), and High-Sensitivity Cardiac Troponin — providing clinicians with a comprehensive biochemical diagnostic platform.

Core Methodologies
Dual-Beam SpectrophotometryIon-Selective Electrode (ISE) PotentiometryWhole-Blood Enzymatic HbA1cAutomated Clot Detection & Liquid Level SensingTurbidimetric Immunoassay (CRP, RF, ASO)Complement Protein Quantification (C3/C4)
Specimen Protocol

Serum separator tube (Gold top / SST) or Lithium Heparin (Green top); EDTA whole blood for HbA1c. Minimum 2–3 mL.

Featured Instrumentation & Equipment Fleet

World-class clinical analyzers powering this division

Beckman Coulter DxC 700 AU

Beckman Coulter
High-Throughput Core Chemistry Analyzer
Capacity & Throughput

Up to 1,200 tests/hour with ISE (800 photometric tests/hr); 150 routine samples + 22 dedicated STAT priority positions.

Core Technology

Digital spectrophotometry, Ion-Selective Electrode (ISE), automated clot detection, and probe crash protection.

Key Features & Capabilities
  • Direct whole-blood HbA1c testing for diabetes screening and monitoring
  • Ultra-low sample volume: 1–25 µL per test to conserve pediatric and geriatric specimens
  • Real-time automated reflex testing, repeat dilutions, and continuous reagent loading
  • Advanced HbA1c measurement with high precision across the clinically critical diabetic monitoring range

Beckman Coulter AU480

Beckman Coulter
Automated Clinical Chemistry & Rapid STAT Analyzer
Capacity & Throughput

Up to 800 tests/hour with ISE (400 photometric tests/hr); 80-rack routine capacity + 22 STAT samples.

Core Technology

Dual-beam spectrophotometry and rapid ~8.5-minute analytical reaction time for urgent specimens.

Key Features & Capabilities
  • High analytical precision across liver, renal, and cardiac enzyme profiles
  • Automated liquid-level sensing and specimen integrity verification
  • Primary tube sampling with internal barcode tracking

Clinical Assay Menu & Test Panels

Complete testing capabilities available in this division

Metabolic & Glycemic Monitoring

  • Fasting Blood Glucose
  • Whole-Blood HbA1c (Advanced Glycated Hemoglobin)
  • Uric Acid
  • Serum Lactate

Renal Function Profiles

  • Urea / Blood Urea Nitrogen (BUN)
  • Serum Creatinine
  • BUN/Creatinine Ratio
  • Estimated GFR (eGFR)

Liver Function & Hepatic Enzymes

  • AST (SGOT)
  • ALT (SGPT)
  • Gamma-Glutamyl Transferase (GGT)
  • Alkaline Phosphatase (ALP)
  • Total Bilirubin & Direct Bilirubin
  • Total Protein & Albumin
  • Albumin/Globulin Ratio

Lipid & Cardiovascular Risk

  • Total Cholesterol
  • HDL Cholesterol
  • LDL Cholesterol (Calculated/Direct)
  • Triglycerides
  • Cardiac Risk Ratios

Electrolyte Balance (ISE)

  • Sodium (Na+)
  • Potassium (K+)
  • Chloride (Cl-)
  • Serum Calcium & Phosphorus

Inflammation & Autoimmune Markers

  • C-Reactive Protein (CRP) — High Sensitivity
  • Rheumatoid Factor (RF)
  • Anti-Streptolysin O (ASO)
  • Complement C3 & C4
  • IgA (Immunoglobulin A)

Cardiac Injury Markers

  • High-Sensitivity Cardiac Troponin I (hs-cTnI)
  • CK-NAC (Total Creatine Kinase)
  • CK-MB Mass (Cardiac Isoenzyme)

Analytical Advantages & Special Capabilities

STAT Emergency turnaround with priority analytical bypass within 45 minutes

Micro-sampling technology (1–25 µL) ideal for pediatric and neonate collections

Automated secondary dilution and out-of-range verification without technician hands-on

Simultaneous multi-panel reflex workflows for comprehensive metabolic screening

Academic Partnership

MLT/MLS Student Hands-On Training

MLT/MLS students enrolled at ECUSTA will gain direct, supervised hands-on experience on both the AU480 and DxC 700 AU analyzers — operating real reagent systems, performing calibration runs, monitoring quality control charts (Westgard multi-rule), and interpreting clinical chemistry results under the supervision of licensed clinical laboratory scientists.

ECUSTA MLT/MLS Academic ProgramView Academic Program
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Request Testing from This Division

Submit an inquiry for Clinical Chemistry testing, or speak with our clinical coordinator for custom panel design and assay feasibility evaluation.